RESUMO
OBJETIVO: Determinar a associação entre a administração pré-operatória de estatina e o delírium pós-operatório em uma corte prospectiva de pacientes submetidos à cirurgia cardíaca. MÉTODOS: Foram analisados pacientes adultos internados na unidade de terapia intensiva após cirurgia cardíaca entre janeiro e junho de 2011. A triagem para delirium foi realizada utilizando o Confusion Assessment Method para analisar delirium em uma unidade de terapia intensiva (CAM-ICU) e Delirium Screening Checklist para terapia intensiva (ICDSC) durante a internação na terapia intensiva RESULTADOS: Cento e sessenta e nove pacientes foram submetidos à cirurgia cardíaca eletiva, dos quais 40,2% estavam utilizando estatina no pré-operatório. Delirium foi identificado em 14,9% dos pacientes que não utilizavam estatina comparado com 11,8% dos que utilizavam (p=0,817) quando avaliados pelo CAM-ICU. Utilizando o ICDSC 18,8% dos pacientes que não usam estatina comparado com 10.3% dos que usam (p=0,191). CONCLUSÃO: Não há relação entre uso de estatinas com a ocorrência de delirium em pacientes submetidos a cirurgia cardíaca.
OBJECTIVE: To determine the association between the preoperative administration of statins and postoperative delirium in a prospective cohort of patients undergoing cardiac surgery. METHODS: All adult patients who were admitted to the intensive care unit following cardiac surgery between January and June 2011 were included. Delirium was screened during the postoperative period using the Confusion Assessment Method for Intensive Care Unit (CAM-ICU) and Intensive Care Delirium Screening Checklist (ICDSC). RESULTS: A total of 169 patients underwent elective cardiac surgery, and 40.2% of the patients were treated preoperatively with statins. Delirium was identified using the CAM-ICU in 14.9% of patients not taking preoperative statins in comparison with 11.8% of the patients taking statins (p = 0.817). Using the ICDSC, delirium was identified in 18.8% of patients not taking statins in comparison with 10.3% of the patients taking statins (p = 0.191). CONCLUSION: The use of preoperative statins is not correlated with postoperative delirium in patients undergoing cardiac surgery.
RESUMO
OBJECTIVE: To determine the association between the preoperative administration of statins and postoperative delirium in a prospective cohort of patients undergoing cardiac surgery. METHODS: All adult patients who were admitted to the intensive care unit following cardiac surgery between January and June 2011 were included. Delirium was screened during the postoperative period using the Confusion Assessment Method for Intensive Care Unit (CAM-ICU) and Intensive Care Delirium Screening Checklist (ICDSC). RESULTS: A total of 169 patients underwent elective cardiac surgery, and 40.2% of the patients were treated preoperatively with statins. Delirium was identified using the CAM-ICU in 14.9% of patients not taking preoperative statins in comparison with 11.8% of the patients taking statins (p = 0.817). Using the ICDSC, delirium was identified in 18.8% of patients not taking statins in comparison with 10.3% of the patients taking statins (p = 0.191). CONCLUSION: The use of preoperative statins is not correlated with postoperative delirium in patients undergoing cardiac surgery.
